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There was an increased number of slices with intraplaque hemorrhage (0.9☑.6 versus 0.3☐.8, P=0.002) and lipid‐rich necrotic core (1.4☑.9 versus 0.8☑.4, P=0.016) and a higher prevalence of plaques with a thin and/or ruptured fibrous cap (32% versus 17%, P=0.023) at the symptomatic side.Ītherosclerosis of the carotid artery accounts for about one fifth of ischemic strokes. We found significantly lower K trans in the symptomatic carotid plaque compared with the asymptomatic side (0.057☐.002 min −1 versus 0.062☐.002 min −1 P=0.033). Presence of a lipid-rich necrotic core, intraplaque hemorrhage, and a thin and/or ruptured fibrous cap was assessed on multisequence magnetic resonance imaging. The volume transfer coefficient K trans, indicative for microvascular density, flow, and permeability, was calculated for the ipsilateral and asymptomatic plaque, using a pharmacokinetic model (Patlak). Stroke: Vascular and Interventional NeurologyĮighty-eight patients with recent transient ischemic attack or ischemic stroke and ipsilateral >2 mm carotid plaque underwent 3 T magnetic resonance imaging to identify plaque components and to determine characteristics of plaque microvasculature.Journal of the American Heart Association (JAHA).Circ: Cardiovascular Quality & Outcomes.Arteriosclerosis, Thrombosis, and Vascular Biology (ATVB).